Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity

Franck Mauvais-Jarvis


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The book provides a reference for years to come, written by world-renowned expert investigators studying sex differences, the role of sex hormones, the systems biology of sex, and the genetic contribution of sex chromosomes to metabolic homeostasis and diseases. In this volume, leaders of the pharmaceutical industry present their views on sex-specific drug discovery. Many of the authors presented at the Keystone Symposium on “Sex and gender factors affecting metabolic homeostasis, diabetes and obesity” to be held in March 2017 in Lake Tahoe, CA. This book will generate new knowledge and ideas on the importance of gender biology and medicine from a molecular standpoint to the population level and to provide the methods to study them. It is intended to be a catalyst leading to gender-specific treatments of metabolic diseases.

There are fundamental aspects of metabolic homeostasis that are regulated differently in males
and females, and influence boththe development of diabetes and obesity and the response to pharmacological intervention. Still, most preclinical researchers avoid studying female rodents due to the added complexity of research plans. The consequence is a generation of data that risks being relevant to only half of the population. This is a timely moment to publish a book on sex differences in diseases as NIH leadership has asked scientists to consider sex as a biological variable in preclinical research, to ensure that women get the same benefit of medical research as men. 

Détails
Auteur
Franck  Mauvais-Jarvis
Marque
Springer
Collection
Advances in Experimental Medicine and Biology
Parution
2017-12-08
Pages
627 pages
EAN papier
9783319701776
Langue
Anglais
Informations ebook
EAN PDF
9783319701783
Prix
304,89 €
En savoir plus
Nb pages copiables 6
Nb pages imprimables 62
Taille du fichier 13660 Ko
Ce livre est accessible aux handicaps   Informations sur l'accessibilité
EAN EPUB
9783319701783
Prix
304,89 €
En savoir plus
Nb pages copiables 6
Nb pages imprimables 62
Taille du fichier 3799 Ko
Ce livre est accessible aux handicaps   Informations sur l'accessibilité
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Defaut-Illustration Franck Mauvais-Jarvis
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