Genomics and Health in the Developing World

Dhavendra Kumar

Genomics and Health in the Developing World provides detailed and comprehensive coverage of population structures, human genomics, and genome variation--with particular emphasis on medical and health issues--in the emerging economies and countries of the developing...

Philosophy of Behavioral Biology

Kathryn S. Plaisance , Thomas A.C. Reydon

This volume provides a broad overview of issues in the philosophy of behavioral biology, covering four main themes: genetic, developmental, evolutionary, and neurobiological explanations of behavior. It is both interdisciplinary and empirically informed in its approach,...

The Practical Guide to the Genetic Family History

Robin L. Bennett

HELPS YOU DEVELOP AND ASSESS PEDIGREES TO MAKE DIAGNOSES, EVALUATE RISK, AND COUNSEL PATIENTS The Second Edition of The Practical Guide to the Genetic Family History not only shows how to take a medical-family history and record a pedigree, but also explains why each...

Achieving Justice in Genomic Translation

Collectif

This book explores implicit choices made by researchers, policy makers, and funders regarding who benefits from society's investment in health research. The authors focus specifically on genetic research and examine whether such research tends to reduce or exacerbate...

Phenotypic Variation

Moyra Smith

During the past two decades international collaborative studies have yielded extensive information on genome sequences, genome architecture and their variations. The challenge we now face is to understand how these variations impact structure and function of organelles,...

Epigenetics and Disease

Susan M. Gasser , En Li

Epigenetics has emerged recently as an important area of molecular biological studies. Epigenetic modifications lead to potentially heritable but reversible alterations in the expression of genes that determine cell fate. Epigenetic misregulation is thus often linked to...

Genetic Disorders Among Arab Populations

Ahmad S. Teebi

Arab populations have their “own” genetic disorders, both universal and particular. Genetic diversity within these source populations, along with the fact that the rates of inbreeding are often high and family sizes are often large, constitute conditions that...

Family Communication about Genetics

Carma L. Bylund , Clara L. Gaff

Genetics is in all senses a family affair. The diagnosis of a genetic condition affects not only the patient and biological family members who may themselves be at risk, but also "family" more generally as support may be sought from those considered kin and who may or...

Management of Genetic Syndromes

Judith E. Allanson , Suzanne B. Cassidy

The American Journal of Medical Genetics heralded the first edition of Management of Genetic Syndromes as an "unparalleled collection of knowledge." Since the first edition's publication, advances have been made in diagnosis, understanding, and treatment of genetic...

Born Entrepreneurs, Born Leaders

Scott Shane

It's no secret that your genes have a subtle, but powerful impact on your job and career. But did you know that your DNA accounts for one third of the difference between you and your co-workers in many aspects of work life, from job satisfaction to income level? That's...

Human Genome Epidemiology, 2nd Edition

Collectif

The first edition of Human Genome Epidemiology, published in 2004, discussed how the epidemiologic approach provides an important scientific foundation for studying the continuum from gene discovery to the development, applications and evaluation of human genome...

Biochemistry of Human Genetics

Cecilia M. O'connor , G. E. W. Wolstenholme

The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results.The Novartis...

Essentials of Medical Genomics

Stuart M. Brown , John G. Hay , Harry Ostrer

Six new chapters on vital topics of interest such as multilocus SNP genotyping (SNP chips), RNAi, ChIP-chip, and genomic tiling arrays New edition responds to reviewers' and users' desire for greater coverage—now the most useful handbook on the market! Practical,...

A Short History of Medical Genetics

Peter S. Harper

An eminent geneticist, veteran author, OMMG Series Editor, and noted archivist, Peter Harper presents a lively account of how our ideas and knowledge about human genetics have developed over the past century from the perspective of someone inside the field with a deep...

Translational Research in Genetics and Genomics

Moyra Smith

Genomics and Clinical Medicine

Dhavendra Kumar , David Weatherall

An important milestone in medicine has been the recent completion of the Human Genome Project. The identification of 30,000 genes and their regulatory proteins provides the framework for understanding the metabolic basis of disease. This advance has also laid the...

Introduction to Risk Calculation in Genetic Counseling

Ian D. Young

The process of genetic counseling involves many key components, such as taking a family genetic history, making a diagnosis, and providing communication and support to the family. Among these core processes is the mathematical calculation of the actual risk of a...

DNA Methylation: Development, Genetic Disease and Cancer

Petra Böhm , Walter Doerfler

It has become apparent that the genomes of many organisms are characterized by unique patterns of DNA methylation which can differ from genome segment to genome segment and cell type to cell type. These patterns can be instrumental in determining cell type and function....

DNA Methylation: Basic Mechanisms

Petra Böhm , Walter Doerfler

Mental Retardation and Developmental Delay

Moyra Smith

Recent advances in neuroscience and genetics have greatly expanded our understanding of the brain and of the etiological factors involved in developmental delay and mental retardation. At the same time, the human genome project has yielded a wealth of information on DNA...