Biographie et livres d'Alphonse E. Sirica

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Alphonse E. Sirica, PhD, MS received his PhD degree in Biomedical Science from the University of Connecticut and his MS degree in Biology from Fordham University. After completing his Postdoctoral training in experimental oncology (liver carcinogenesis) with Dr. Henry C. Pitot at the McArdle Laboratory for Cancer Research at the University of Wisconsin-Madison, he remained as faculty at the University of Wisconsin School of Medicine from 1979 to 1984. In June 1984, he joined the VCU Department of Pathology faculty to develop a program in Experimental Pathology and in 1990 was promoted to the rank of full professor with tenure. From 1993 to 1999, he served as Chair of the Division of Experimental Pathology in the Department of Pathology. In 1999, he founded the Department's Division of Cellular and Molecular Pathogenesis and continued to serve as Division Chair for another 15 years, stepping down from this position in July 2014 to devote full time to his NIH funded research program. In 2019, he was appointed to a Distinguished Career Professorship at Virginia Commonwealth University and in 2020 appointed Professor Emeritus of Pathology at VCU.Dr. Sirica is an internationally recognized biomedical researcher and scholar in the areas of liver carcinogenesis, cholangiocyte biology and pathobiology, and cholangiocarcinoma, with extensive experience and expertise in cell and molecular cholangiocarcinogenesis and preclinical experimental therapeutics of cholangiocarcinoma. As principal investigator, Dr. Sirica had been funded by the National Cancer Institute of the National Institutes of Health for 37 years. In June 2019, he was recognized by Expertscape as an Expertscape World Expert in Cholangiocarcinoma. He has previously edited four books on topics including the pathobiology of neoplasia, cellular and molecular pathogenesis, hepatocarcinogenesis, and bile duct pathobiology and pathophysiology, and has published in journals such as Proceedings of the National Academy of Science USA, Cancer Research, Hepatology, Gastroenterology, Nature Reviews Gastroenterology & Hepatology, Hepatology Research, Nature Reviews Disease Primers, Hepatology Communications, and the American Journal of Pathology. He has organized several national conferences on hepatobiliary cancers, most recently a Keystone Symposium titled “Hepatobiliary Cancers: Pathobiology and Translational Advances?, which was held as a Keystone e-symposium in March 22-24, 2021, as well as a FASEB Catalyst Conference titled “Cholangiocarcinoma: Molecular Drivers, Microenvironment, and Precision Medicine? held as a virtual event on April 7, 2021. Currently, he is serving as primary organizer of an approved 2023 FASEB Science Research Conference, “The Cholangiocarcinoma Conference: Molecular Drivers, Microenvironment, and Precision Medicine?.

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Hepatobiliary Cancers: Translational Advances and Molecular Medicine

Paul B. Fisher , Alphonse E. Sirica

Academic Press

2022-08-10

PDF, epub sans DRM

Hepatobiliary cancer refers to primary malignant tumors originating in cells of the liver, bile ducts, and gallbladder. Globally, primary liver cancer, which includes hepatocellular carcinoma (~75 % of all cases) and intrahepatic biliary cancer or...

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