As part of his work, Dr. de Vries conducts research on adolescent health (sexual and reproductive, adolescent mental health, bullying in adolescents, health and education systems for adolescents, and intimate partner violence in adolescents), autism (screening and diagnostic tool evaluation and development, evaluation and development of interventions, health and education systems, and use of technology), and tuberous sclerosis complex (TSC-assocationed neuropsychiatric disorders, clinical trials of mTOR inhibitors, and natural history of TSC).