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Group-Sequential Clinical Trials with Multiple Co-Objectives


Koko Asakura , Scott R. Evans , Toshimitsu Hamasaki , Toshimitsu Ochiai


This book focuses on group sequential methods for clinical trials with co-primary endpoints based on the decision-making frameworks for: (1) rejecting the null hypothesis (stopping for efficacy), (2) rejecting the alternative hypothesis (stopping for futility), and (3)...

Parution : 2016-06-01
Format(s) : ePub
Éditeur : Springer
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